Genital Warts

The war against the Human Papilloma Virus rages on as scientists try to find better ways of detecting the virus and understanding infection outcomes. The virus has been established as a cause of cervical cancer beyond doubt. Researchers have now directed their attention to the different methods by which they can detect the virus within the cells of the cervix. The cervix is the moth of the womb and the most vulnerable area to cancerous transformation after an hpv infection. Flourescence in situ hybridization hpv offers new hope to detect the infection and arrest the progress of the condition to cancer.

The fluorescence in situ hybridization hpv is also called a biopsy or in situ hybridization for HPV. The aim of the test is not just to detect the presence of the HPv virus. It also helps the clinician to determine the type of HPV DNA sequences in the tissue biopsies. The type of DNA detected will indicate the strain of the virus which has infected the tissue and this is a marker for the prognosis of the patient. For this test the sample required is usually a tissue block or a tissue biopsy which has been preserved in formalin. The tissue block or sample will be taken by your doctor in an outpatient procedure. The procedure does not usually require any form of anesthesia and in most cases local anesthesia is sufficient.

For fluorescence in situ hybridization hpv at least enough tissue for eight 5 micron sections must be submitted for a good report. The tissue is submitted for testing after it has been embedded in a paraffin block. This is made when the tissue biopsy removed by your doctor is transferred from the formalin in which it was kept, to a paraffin block. The sample will be rejected if there is insuffiicent tissue or the tissue has been taken from the wrong part of the cervix. The tissue sample may also be rejected if it has not been fixed properly by the formalin.

The fluorescence in situ hybridization hpv is an excellent test to determine the type of HPV. It helps to confirm the presence of an HPV infection and clears doubts about a sample in case the histology report was not conclusive. More than 70 distinct HPV types have been isolated from the anogenital mucosa. This test provides a qualitative molecular detection of 13 different types of HPV in cervical or oral mucosal specimens. The HPV in situ hybridization assay helps clinicians distinguish between two HPV DNA groups. These groups have different prognostic outcomes in the mucosal tissue. The low risk types are 6 and 11. The high risk hpv viruses are 16, 18, 31, 33, 35, 45, 51, 52, 56, 58 and 66. In genital lesions infected by human papillomavirus (HPV). histological criteria and HPV DNA typing are of prognostic value Methods such as in situ hybridization are used extensively since they preserve the histological organization of the tissue, and allow the detection and characterization of HPV DNA.

Karl Dorads - GenitalWartsSite.com